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D-Aspartate Depletion Perturbs Steroidogenesis and Spermatogenesis in Mice

High levels of free D-aspartate (D-Asp) are present in vertebrate testis during post-natal development, coinciding with the onset of testosterone production, which suggests that this atypical amino acid might participate in the regulation of hormone biosynthesis. To elucidate the unknown role of D-A...

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Detalles Bibliográficos
Autores principales: Santillo, Alessandra, Falvo, Sara, Venditti, Massimo, Di Maio, Anna, Chieffi Baccari, Gabriella, Errico, Francesco, Usiello, Alessandro, Minucci, Sergio, Di Fiore, Maria Maddalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136051/
https://www.ncbi.nlm.nih.gov/pubmed/37189369
http://dx.doi.org/10.3390/biom13040621