A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and Is Upregulated during Hypoxia and Aging

The platelet-derived growth factor-BB (PDGF-BB) pathway provides critical regulation of cerebrovascular pericytes, orchestrating their investment and retention within the brain microcirculation. Dysregulated PDGF Receptor-beta (PDGFRβ) signaling can lead to pericyte defects that compromise blood-bra...

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Detalles Bibliográficos
Autores principales: Payne, Laura Beth, Abdelazim, Hanaa, Hoque, Maruf, Barnes, Audra, Mironovova, Zuzana, Willi, Caroline E., Darden, Jordan, Houk, Clifton, Sedovy, Meghan W., Johnstone, Scott R., Chappell, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136073/
https://www.ncbi.nlm.nih.gov/pubmed/37189457
http://dx.doi.org/10.3390/biom13040711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136073/
https://www.ncbi.nlm.nih.gov/pubmed/37189457
http://dx.doi.org/10.3390/biom13040711

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