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Replacement, Reduction, and Refinement of Animal Experiments in Anticancer Drug Development: The Contribution of 3D In Vitro Cancer Models in the Drug Efficacy Assessment

In the last decades three-dimensional (3D) in vitro cancer models have been proposed as a bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold standards in the preclinical assessment of anticancer drug efficacy. 3D in vitro cancer models can be generated through a mult...

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Detalles Bibliográficos
Autores principales: Tosca, Elena M., Ronchi, Davide, Facciolo, Daniele, Magni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136119/
https://www.ncbi.nlm.nih.gov/pubmed/37189676
http://dx.doi.org/10.3390/biomedicines11041058