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Celastrol Supplementation Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice

Background: Abdominal aortic aneurysms (AAAs) are permanent dilations of the abdominal aorta with 4–5 times greater prevalence in males than in females. The aim of this study is to define whether Celastrol, a pentacyclic triterpene from the root extracts of Tripterygium wilfordii, supplementation in...

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Detalles Bibliográficos
Autores principales: Javidan, Aida, Jiang, Weihua, Yang, Lihua, Frony, Ana Clara, Subramanian, Venkateswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136124/
https://www.ncbi.nlm.nih.gov/pubmed/37189351
http://dx.doi.org/10.3390/biom13040603