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Human-Derived Cortical Neurospheroids Coupled to Passive, High-Density and 3D MEAs: A Valid Platform for Functional Tests

With the advent of human-induced pluripotent stem cells (hiPSCs) and differentiation protocols, methods to create in-vitro human-derived neuronal networks have been proposed. Although monolayer cultures represent a valid model, adding three-dimensionality (3D) would make them more representative of...

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Detalles Bibliográficos
Autores principales: Muzzi, Lorenzo, Di Lisa, Donatella, Falappa, Matteo, Pepe, Sara, Maccione, Alessandro, Pastorino, Laura, Martinoia, Sergio, Frega, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136157/
https://www.ncbi.nlm.nih.gov/pubmed/37106636
http://dx.doi.org/10.3390/bioengineering10040449