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Blood–Brain Barrier Integrity Is Perturbed in a Mecp2-Null Mouse Model of Rett Syndrome

Rett syndrome (RTT, online MIM 312750) is a devastating neurodevelopmental disorder characterized by motor and cognitive disabilities. It is mainly caused by pathogenetic variants in the X-linked MECP2 gene, encoding an epigenetic factor crucial for brain functioning. Despite intensive studies, the...

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Detalles Bibliográficos
Autores principales: Pepe, Giuseppe, Fioriniello, Salvatore, Marracino, Federico, Capocci, Luca, Maglione, Vittorio, D’Esposito, Maurizio, Di Pardo, Alba, Della Ragione, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136210/
https://www.ncbi.nlm.nih.gov/pubmed/37189354
http://dx.doi.org/10.3390/biom13040606