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I(Ks) Activator ML277 Mildly Affects Repolarization and Arrhythmic Outcome in the CAVB Dog Model

Long QT syndrome type 1 with affected I(Ks) is associated with a high risk for developing Torsade de Pointes (TdP) arrhythmias and eventually sudden cardiac death. Therefore, it is of high interest to explore drugs that target I(Ks) as antiarrhythmics. We examined the antiarrhythmic effect of I(Ks)...

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Detalles Bibliográficos
Autores principales: van Bavel, Joanne J. A., Beekman, Henriëtte D. M., Smoczyńska, Agnieszka, van der Heyden, Marcel A. G., Vos, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136248/
https://www.ncbi.nlm.nih.gov/pubmed/37189765
http://dx.doi.org/10.3390/biomedicines11041147