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Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin Treatment

Beyond sleep/wake, clock genes regulate the daily rhythms of melatonin production, motor activity, innate immunity, and mitochondrial dynamics, among others. All these rhythms are affected in Parkinson’s disease (PD), suggesting that chronodisruption may be an early stage of the disease. The aim of...

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Detalles Bibliográficos
Autores principales: Aranda-Martínez, Paula, Fernández-Martínez, José, Ramírez-Casas, Yolanda, Rodríguez-Santana, César, Rusanova, Iryna, Escames, Germaine, Acuña-Castroviejo, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136267/
https://www.ncbi.nlm.nih.gov/pubmed/37107331
http://dx.doi.org/10.3390/antiox12040954