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KDELC2 Upregulates Glioblastoma Angiogenesis via Reactive Oxygen Species Activation and Tumor-Associated Macrophage Proliferation

Glioblastoma is notorious for its rapid progression and neovascularization. In this study, it was found that KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2) stimulated vasculogenic factor expression and induced human umbilical vein endothelial cell (HUVEC) proliferation. The NLRP3 inflammasome and auto...

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Detalles Bibliográficos
Autores principales: Tsai, Yu-Ling, Chen, Ying, Chen, Ying-Chuan, Tsai, Wen-Chiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136350/
https://www.ncbi.nlm.nih.gov/pubmed/37107298
http://dx.doi.org/10.3390/antiox12040923