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Do Elevated YKL-40 Levels Drive the Immunosuppressive Tumor Microenvironment in Colorectal Cancer? Assessment of the Association of the Expression of YKL-40, MMP-8, IL17A, and PD-L1 with Coexisting Type 2 Diabetes, Obesity, and Active Smoking

The influence of chitinase-3-like protein 1 (YKL-40 or CHI3L1) expression on the immunological properties of the tumor microenvironment, which may affect the effectiveness of immunotherapy, is currently not sufficiently understood in colorectal cancer (CRC). The aim of this study was to investigate...

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Detalles Bibliográficos
Autores principales: Ochman, Błażej, Mielcarska, Sylwia, Kula, Agnieszka, Dawidowicz, Miriam, Robotycka, Julia, Piecuch, Jerzy, Szrot, Monika, Dzięgielewska-Gęsiak, Sylwia, Muc-Wierzgoń, Małgorzata, Waniczek, Dariusz, Świętochowska, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136442/
https://www.ncbi.nlm.nih.gov/pubmed/37185706
http://dx.doi.org/10.3390/cimb45040182