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Do Elevated YKL-40 Levels Drive the Immunosuppressive Tumor Microenvironment in Colorectal Cancer? Assessment of the Association of the Expression of YKL-40, MMP-8, IL17A, and PD-L1 with Coexisting Type 2 Diabetes, Obesity, and Active Smoking
The influence of chitinase-3-like protein 1 (YKL-40 or CHI3L1) expression on the immunological properties of the tumor microenvironment, which may affect the effectiveness of immunotherapy, is currently not sufficiently understood in colorectal cancer (CRC). The aim of this study was to investigate...
Autores principales: | Ochman, Błażej, Mielcarska, Sylwia, Kula, Agnieszka, Dawidowicz, Miriam, Robotycka, Julia, Piecuch, Jerzy, Szrot, Monika, Dzięgielewska-Gęsiak, Sylwia, Muc-Wierzgoń, Małgorzata, Waniczek, Dariusz, Świętochowska, Elżbieta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136442/ https://www.ncbi.nlm.nih.gov/pubmed/37185706 http://dx.doi.org/10.3390/cimb45040182 |
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