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Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease

A mis-metabolism of transition metals (i.e., copper, iron, and zinc) in the brain has been recognised as a precursor event for aggregation of Amyloid-β plaques, a pathological hallmark of Alzheimer’s disease (AD). However, imaging cerebral transition metals in vivo can be extremely challenging. As t...

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Detalles Bibliográficos
Autores principales: Hosseinpour Mashkani, Seyed Mostafa, Bishop, David P., Raoufi-Rad, Newsha, Adlard, Paul A., Shimoni, Olga, Golzan, S. Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136451/
https://www.ncbi.nlm.nih.gov/pubmed/37190053
http://dx.doi.org/10.3390/cells12081144