Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer

Poor visualization of polyps can limit colorectal cancer screening. Fluorescent antibodies to mucin5AC (MUC5AC), a glycoprotein upregulated in adenomas and colorectal cancer, could improve screening colonoscopy polyp detection rate. Adenomatous polyposis coli flox mice with a Cdx2-Cre transgene (CPC...

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Detalles Bibliográficos
Autores principales: Turner, Michael A., Cox, Kristin E., Liu, Shanglei, Neel, Nicholas, Amirfakhri, Siamak, Nishino, Hiroto, Hosseini, Mojgan, Alcantara, Joshua A., Abd El-Hafeez, Amer Ali, Lwin, Thinzar M., Mallya, Kavita, Pisegna, Joseph R., Singh, Satish K., Ghosh, Pradipta, Hoffman, Robert M., Batra, Surinder K., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136452/
https://www.ncbi.nlm.nih.gov/pubmed/37185743
http://dx.doi.org/10.3390/cimb45040219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136452/
https://www.ncbi.nlm.nih.gov/pubmed/37185743
http://dx.doi.org/10.3390/cimb45040219

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