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Down Syndrome Altered Cell Composition in Blood, Brain, and Buccal Swab Samples Profiled by DNA-Methylation-Based Cell-Type Deconvolution

Down syndrome (DS) is a genetic disorder caused by an extra copy of chromosome 21 that presents developmental dysfunction and intellectual disability. To better understand the cellular changes associated with DS, we investigated the cell composition in blood, brain, and buccal swab samples from DS p...

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Detalles Bibliográficos
Autores principales: Zhang, Ze, Stolrow, Hannah G., Christensen, Brock C., Salas, Lucas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136493/
https://www.ncbi.nlm.nih.gov/pubmed/37190077
http://dx.doi.org/10.3390/cells12081168