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Nuclear and Cytoplasmic hTERT, Tumor-Infiltrating Lymphocytes, and Telomere Elongation Leukocytes Are Independent Factors in the Response to Neoadjuvant Treatment in HER2-Enriched Breast Cancer

HER2-enriched tumors are responsible for 20% of breast tumors and have high rates of immune infiltrates in the tumor stroma that respond favorably to neoadjuvant chemotherapy. In the context of tumors, telomeres control cell death and prevent tumor cells from replicating discontinuously, leading to...

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Detalles Bibliográficos
Autores principales: Delmonico, Lucas, Bines, José, do Nascimento, Cristina Moreira, Fernandes, Priscila Valverde, Barbosa, Isabel de Souza, Ribeiro, Gabriel Brito, de Paula, Bruno Henrique Rala, Silvestre, Rafaele Tavares, Ornellas, Maria Helena Faria, Alves, Gilda, Lage, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136514/
https://www.ncbi.nlm.nih.gov/pubmed/37185424
http://dx.doi.org/10.3390/curroncol30040311