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Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery

Enteroviruses are a leading cause of upper respiratory tract, gastrointestinal, and neurological infections. Management of enterovirus-related diseases has been hindered by the lack of specific antiviral treatment. The pre-clinical and clinical development of such antivirals has been challenging, ca...

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Detalles Bibliográficos
Autores principales: Masmoudi, Fatma, Santos-Ferreira, Nanci, Pajkrt, Dasja, Wolthers, Katja C., DeGroot, Jeroen, Vlaming, Maria L. H., Rocha-Pereira, Joana, Buti, Ludovico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136548/
https://www.ncbi.nlm.nih.gov/pubmed/37190047
http://dx.doi.org/10.3390/cells12081138