Overexpression of GREM1 Improves the Survival Capacity of Aged Cardiac Mesenchymal Progenitor Cells via Upregulation of the ERK/NRF2-Associated Antioxidant Signal Pathway

Ischemic heart disease is the leading cause of mortality in the United States. Progenitor cell therapy can restore myocardial structure and function. However, its efficacy is severely limited by cell aging and senescence. Gremlin-1 (GREM1), a member of the bone morphogenetic protein antagonist famil...

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Detalles Bibliográficos
Autores principales: Kaur, Gurleen, Wang, Xiaoliang, Li, Xiuchun, Ong, Hannah, He, Xiangfei, Cai, Chuanxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136744/
https://www.ncbi.nlm.nih.gov/pubmed/37190112
http://dx.doi.org/10.3390/cells12081203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136744/
https://www.ncbi.nlm.nih.gov/pubmed/37190112
http://dx.doi.org/10.3390/cells12081203

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