Metformin Pre-Treatment as a Means of Mitigating Disuse-Induced Rat Soleus Muscle Wasting

Currently, no ideal treatment exists to combat skeletal muscle disuse-induced atrophy and loss of strength. Because the activity of AMP-activated protein kinase (AMPK) in rat soleus muscle is suppressed at the early stages of disuse, we hypothesized that pre-treatment of rats with metformin (an AMPK...

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Detalles Bibliográficos
Autores principales: Mirzoev, Timur M., Paramonova, Inna I., Rozhkov, Sergey V., Kalashnikova, Ekaterina P., Belova, Svetlana P., Tyganov, Sergey A., Vilchinskaya, Natalia A., Shenkman, Boris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136829/
https://www.ncbi.nlm.nih.gov/pubmed/37185725
http://dx.doi.org/10.3390/cimb45040201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136829/
https://www.ncbi.nlm.nih.gov/pubmed/37185725
http://dx.doi.org/10.3390/cimb45040201

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