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Metformin Pre-Treatment as a Means of Mitigating Disuse-Induced Rat Soleus Muscle Wasting

Currently, no ideal treatment exists to combat skeletal muscle disuse-induced atrophy and loss of strength. Because the activity of AMP-activated protein kinase (AMPK) in rat soleus muscle is suppressed at the early stages of disuse, we hypothesized that pre-treatment of rats with metformin (an AMPK...

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Detalles Bibliográficos
Autores principales:	Mirzoev, Timur M., Paramonova, Inna I., Rozhkov, Sergey V., Kalashnikova, Ekaterina P., Belova, Svetlana P., Tyganov, Sergey A., Vilchinskaya, Natalia A., Shenkman, Boris S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136829/ https://www.ncbi.nlm.nih.gov/pubmed/37185725 http://dx.doi.org/10.3390/cimb45040201

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