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Drosophila Models Reveal Properties of Mutant Lamins That Give Rise to Distinct Diseases

Mutations in the LMNA gene cause a collection of diseases known as laminopathies, including muscular dystrophies, lipodystrophies, and early-onset aging syndromes. The LMNA gene encodes A-type lamins, lamins A/C, intermediate filaments that form a meshwork underlying the inner nuclear membrane. Lami...

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Detalles Bibliográficos
Autores principales: Walker, Sydney G., Langland, Christopher J., Viles, Jill, Hecker, Laura A., Wallrath, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136830/
https://www.ncbi.nlm.nih.gov/pubmed/37190051
http://dx.doi.org/10.3390/cells12081142