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Targeting FLT3 Mutation in Acute Myeloid Leukemia: Current Strategies and Future Directions

SIMPLE SUMMARY: FLT3 mutation is commonly present in newly diagnosed patients with acute myeloid leukemia, and confers high relapse risk. Targeted therapies with FLT3 inhibitors improve survival when used as a single agent in a salvage setting, and more so when combined with other therapies in newly...

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Detalles Bibliográficos
Autores principales: Fedorov, Kateryna, Maiti, Abhishek, Konopleva, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136888/
https://www.ncbi.nlm.nih.gov/pubmed/37190240
http://dx.doi.org/10.3390/cancers15082312