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The Antiepileptic Drug Oxcarbazepine Inhibits the Growth of Patient-Derived Isocitrate Dehydrogenase Mutant Glioma Stem-like Cells

SIMPLE SUMMARY: Patients diagnosed with isocitrate dehydrogenase (IDH)-mutated brain tumors frequently suffer from seizures, and the seizures were shown to promote tumor growth. Anti-seizure medications (antiepileptic drugs) might be able to break this vicious circle. However, it is not yet known wh...

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Detalles Bibliográficos
Autores principales: Dao Trong, Philip, Jungwirth, Gerhard, Unterberg, Andreas, Herold-Mende, Christel, Warta, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136933/
https://www.ncbi.nlm.nih.gov/pubmed/37190109
http://dx.doi.org/10.3390/cells12081200