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Histone Deacetylase 4 Inhibition Reduces Rotenone-Induced Alpha-Synuclein Accumulation via Autophagy in SH-SY5Y Cells

(1) Background: Parkinson’s disease (PD) is the most common movement disorder. Imbalanced protein homeostasis and α-syn aggregation are involved in PD pathogenesis. Autophagy is related to the occurrence and development of PD and can be regulated by histone deacetylases (HDACs). Various inhibitors o...

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Detalles Bibliográficos
Autores principales: Wang, Luxi, Liu, Ling, Han, Chao, Jiang, Haiyang, Ma, Kai, Guo, Shiyi, Xia, Yun, Wan, Fang, Huang, Jinsha, Xiong, Nian, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136981/
https://www.ncbi.nlm.nih.gov/pubmed/37190635
http://dx.doi.org/10.3390/brainsci13040670