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Temozolomide and Lomustine Induce Tissue Factor Expression and Procoagulant Activity in Glioblastoma Cells In Vitro

SIMPLE SUMMARY: Cancer patients, particularly with glioblastoma (GBM), are at increased risk for thrombosis. This risk is further increased upon treatment with chemotherapy. Tissue factor (TF) is the initiator of the extrinsic coagulation pathway and expressed by GBM cells. Chemotherapy is known to...

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Detalles Bibliográficos
Autores principales: Kapteijn, Maaike Y., Zwaan, Shanna, ter Linden, Esther, Laghmani, El Houari, van den Akker, Rob F. P., Rondon, Araci M. R., van der Zanden, Sabina Y., Neefjes, Jacques, Versteeg, Henri H., Buijs, Jeroen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137012/
https://www.ncbi.nlm.nih.gov/pubmed/37190275
http://dx.doi.org/10.3390/cancers15082347