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Metformin Protects Radiation-Induced Early Brain Injury by Reducing Inflammation and DNA Damage

Radiation-induced brain injury (RIBI) is one of the most common and fatal complications of cranial radiation therapy (CRT); however, no effective intervention is available currently. Metformin has been reported to have anti-RIBI activity as a first-line anti-diabetic drug. However, the mechanism of...

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Detalles Bibliográficos
Autores principales: Xiang, Jiabao, Lu, Yiming, Quan, Cheng, Gao, Yan, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137040/
https://www.ncbi.nlm.nih.gov/pubmed/37190610
http://dx.doi.org/10.3390/brainsci13040645