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Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer

SIMPLE SUMMARY: Radiotherapy is a cornerstone for the treatment of colorectal cancer. Tumor cells present in an environment lacking oxygen (hypoxia) are resistant, leading to patient relapse. Altering redox homeostasis and inducing cell death of hypoxic cancer cells is a promising strategy to overco...

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Detalles Bibliográficos
Autores principales: Kerkhove, Lisa, Geirnaert, Febe, Rifi, Amir Laraki, Law, Ka Lun, Gutiérrez, Adrián, Oudaert, Inge, Corbet, Cyril, Gevaert, Thierry, Dufait, Inès, De Ridder, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137052/
https://www.ncbi.nlm.nih.gov/pubmed/37190291
http://dx.doi.org/10.3390/cancers15082363