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Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer
SIMPLE SUMMARY: Radiotherapy is a cornerstone for the treatment of colorectal cancer. Tumor cells present in an environment lacking oxygen (hypoxia) are resistant, leading to patient relapse. Altering redox homeostasis and inducing cell death of hypoxic cancer cells is a promising strategy to overco...
Autores principales: | Kerkhove, Lisa, Geirnaert, Febe, Rifi, Amir Laraki, Law, Ka Lun, Gutiérrez, Adrián, Oudaert, Inge, Corbet, Cyril, Gevaert, Thierry, Dufait, Inès, De Ridder, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137052/ https://www.ncbi.nlm.nih.gov/pubmed/37190291 http://dx.doi.org/10.3390/cancers15082363 |
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