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Set Protein Is Involved in FLT3 Membrane Trafficking
SIMPLE SUMMARY: Internal tandem duplication mutations in the FLT3 tyrosine kinase receptor (FLT3-ITD) are associated with poor prognosis in patients with acute myeloid leukemia. These mutations cause constitutive activation of FLT3, altering the underlying signaling pathways and retaining FLT3 in th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137103/ https://www.ncbi.nlm.nih.gov/pubmed/37190162 http://dx.doi.org/10.3390/cancers15082233 |