Set Protein Is Involved in FLT3 Membrane Trafficking

SIMPLE SUMMARY: Internal tandem duplication mutations in the FLT3 tyrosine kinase receptor (FLT3-ITD) are associated with poor prognosis in patients with acute myeloid leukemia. These mutations cause constitutive activation of FLT3, altering the underlying signaling pathways and retaining FLT3 in th...

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Detalles Bibliográficos
Autores principales: Marcotegui, Nerea, Romero-Murillo, Silvia, Marco-Sanz, Javier, Peris, Irene, Berrozpe, Blanca S., Vicente, Carmen, Odero, María D., Arriazu, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137103/
https://www.ncbi.nlm.nih.gov/pubmed/37190162
http://dx.doi.org/10.3390/cancers15082233

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