Lipopolysaccharide Preconditioning Restricts Microglial Overactivation and Alleviates Inflammation-Induced Depressive-like Behavior in Mice

Overactive microglia and severe neuroinflammation play crucial roles in the development of major depressive disorder. Preconditioning with lipopolysaccharide (LPS) provides protection against severe neuroinflammation. However, administering high doses of LPS to mice triggers depressive symptoms. The...

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Detalles Bibliográficos
Autores principales: Yu, Haiping, Kan, Junli, Tang, Mingming, Zhu, Yanbing, Hu, Baoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137116/
https://www.ncbi.nlm.nih.gov/pubmed/37190515
http://dx.doi.org/10.3390/brainsci13040549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137116/
https://www.ncbi.nlm.nih.gov/pubmed/37190515
http://dx.doi.org/10.3390/brainsci13040549

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