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A Tumor Microenvironment-Driven Network Regulated by STAT3 and p65 Negatively Controls the Enrichment of Cancer Stem Cells in Human HR+/HER2− Breast Cancer

SIMPLE SUMMARY: Hormone receptor-positive (HR+)/HER2− breast cancer is driven by extracellular cues within the tumor microenvironment (TME) including hormonal, inflammatory and growth-stimulating signals. Our past findings indicate that a “TME Stimulation” jointly addressing these three arms induces...

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Detalles Bibliográficos
Autores principales: Ben-Yaakov, Hagar, Meshel, Tsipi, Pasmanik-Chor, Metsada, Körner, Cindy, Ben-Baruch, Adit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137120/
https://www.ncbi.nlm.nih.gov/pubmed/37190183
http://dx.doi.org/10.3390/cancers15082255