Euchromatic Histone Lysine Methyltransferase 2 Inhibition Enhances Carfilzomib Sensitivity and Overcomes Drug Resistance in Multiple Myeloma Cell Lines

SIMPLE SUMMARY: In the last decade, proteasome inhibitors have become a standard treatment for multiple myeloma. However, resistance to combined therapies remains a challenge due to the disease’s complex biology, crosstalk with the bone marrow microenvironment, and toxicities. To address this issue,...

Descripción completa

Detalles Bibliográficos
Autores principales: Mereu, Elisabetta, Abbo, Damiano, Paradzik, Tina, Cumerlato, Michela, Bandini, Cecilia, Labrador, Maria, Maccagno, Monica, Ronchetti, Domenica, Manicardi, Veronica, Neri, Antonino, Piva, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137151/
https://www.ncbi.nlm.nih.gov/pubmed/37190128
http://dx.doi.org/10.3390/cancers15082199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137151/
https://www.ncbi.nlm.nih.gov/pubmed/37190128
http://dx.doi.org/10.3390/cancers15082199

Ejemplares similares