A Novel Hydrogel-Based 3D In Vitro Tumor Panel of 30 PDX Models Incorporates Tumor, Stromal and Immune Cell Compartments of the TME for the Screening of Oncology and Immuno-Therapies

Human-relevant systems that mimic the 3D tumor microenvironment (TME), particularly the complex mechanisms of immuno-modulation in the tumor stroma, in a reproducible and scalable format are of high interest for the drug discovery industry. Here, we describe a novel 3D in vitro tumor panel comprisin...

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Detalles Bibliográficos
Autores principales: Xue, Bin, Schüler, Julia, Harrod, Christopher M., Lashuk, Kanstantsin, Bomya, Zoji, Hribar, Kolin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137152/
https://www.ncbi.nlm.nih.gov/pubmed/37190054
http://dx.doi.org/10.3390/cells12081145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137152/
https://www.ncbi.nlm.nih.gov/pubmed/37190054
http://dx.doi.org/10.3390/cells12081145

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