Mannose Inhibits the Pentose Phosphate Pathway in Colorectal Cancer and Enhances Sensitivity to 5-Fluorouracil Therapy

SIMPLE SUMMARY: 5-fluorouracil (5-FU) has been the treatment of choice against colorectal cancer (CRC) for the past six decades. However, 5-FU exhibits high toxicity and drug resistance in CRC patients, highlighting the need for less toxic and more efficient treatments. The pentose phosphate pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Hadeethi, Sadaf, El-Baba, Chirine, Araji, Khaled, Hayar, Berthe, Cheikh, Israa Ahmad, El-Khoury, Riyad, Usta, Julnar, Darwiche, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137209/
https://www.ncbi.nlm.nih.gov/pubmed/37190196
http://dx.doi.org/10.3390/cancers15082268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137209/
https://www.ncbi.nlm.nih.gov/pubmed/37190196
http://dx.doi.org/10.3390/cancers15082268

Ejemplares similares