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Mannose Inhibits the Pentose Phosphate Pathway in Colorectal Cancer and Enhances Sensitivity to 5-Fluorouracil Therapy

SIMPLE SUMMARY: 5-fluorouracil (5-FU) has been the treatment of choice against colorectal cancer (CRC) for the past six decades. However, 5-FU exhibits high toxicity and drug resistance in CRC patients, highlighting the need for less toxic and more efficient treatments. The pentose phosphate pathway...

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Detalles Bibliográficos
Autores principales:	Al Hadeethi, Sadaf, El-Baba, Chirine, Araji, Khaled, Hayar, Berthe, Cheikh, Israa Ahmad, El-Khoury, Riyad, Usta, Julnar, Darwiche, Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137209/ https://www.ncbi.nlm.nih.gov/pubmed/37190196 http://dx.doi.org/10.3390/cancers15082268

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