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The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo

SIMPLE SUMMARY: When breast cancer (BC) spreads to the skeleton it is no longer curable; new treatments are needed in this setting. When given daily, the CDK4/6 inhibitor palbociclib significantly impedes tumour growth in murine models of both estrogen receptor positive and triple negative bone meta...

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Detalles Bibliográficos
Autores principales: Saleh, Lubaid, Ottewell, Penelope D., Brown, Janet E., Wood, Steve L., Brown, Nichola J., Wilson, Caroline, Park, Catherine, Ali, Simak, Holen, Ingunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137281/
https://www.ncbi.nlm.nih.gov/pubmed/37190140
http://dx.doi.org/10.3390/cancers15082211