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IL-21 (rs2055979 and rs2221903)/IL-21R (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients

Rheumatoid Arthritis (RA) is characterized by joint destruction, chronic inflammation, and autoantibody production. IL-21/IL-21R plays an essential role in the immunopathology of RA. Elevated IL-21 serum levels have been associated with RA and disease activity. Here, we evaluated the association of...

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Detalles Bibliográficos
Autores principales: Carreño-Saavedra, Noemi Magdalena, Reyes-Pérez, Itzel Viridiana, Machado-Sulbaran, Andrea Carolina, Martínez-Bonilla, Gloria Esther, Ramírez-Dueñas, María Guadalupe, Muñoz-Valle, José Francisco, Olaya-Valdiviezo, Valeria, García-Iglesias, Trinidad, Martínez-García, Erika Aurora, Sánchez-Hernández, Pedro Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137781/
https://www.ncbi.nlm.nih.gov/pubmed/37107636
http://dx.doi.org/10.3390/genes14040878