DNA Polymerase Delta Exhibits Altered Catalytic Properties on Lysine Acetylation

DNA polymerase delta is the primary polymerase that is involved in undamaged nuclear lagging strand DNA replication. Our mass-spectroscopic analysis has revealed that the human DNA polymerase δ is acetylated on subunits p125, p68, and p12. Using substrates that simulate Okazaki fragment intermediate...

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Detalles Bibliográficos
Autores principales: Njeri, Catherine, Pepenella, Sharon, Battapadi, Tripthi, Bambara, Robert A., Balakrishnan, Lata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137900/
https://www.ncbi.nlm.nih.gov/pubmed/37107532
http://dx.doi.org/10.3390/genes14040774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137900/
https://www.ncbi.nlm.nih.gov/pubmed/37107532
http://dx.doi.org/10.3390/genes14040774

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