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CRISPR/Cas9 Gene Editing System Can Alter Gene Expression and Induce DNA Damage Accumulation
Clustered regularly interspaced short palindromic repeats (CRISPR) and the associated protein (Cas) gene editing can induce P53 activation, large genome fragment deletions, and chromosomal structural variations. Here, gene expression was detected in host cells using transcriptome sequencing followin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138046/ https://www.ncbi.nlm.nih.gov/pubmed/37107564 http://dx.doi.org/10.3390/genes14040806 |