CRISPR/Cas9 Gene Editing System Can Alter Gene Expression and Induce DNA Damage Accumulation

Clustered regularly interspaced short palindromic repeats (CRISPR) and the associated protein (Cas) gene editing can induce P53 activation, large genome fragment deletions, and chromosomal structural variations. Here, gene expression was detected in host cells using transcriptome sequencing followin...

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Detalles Bibliográficos
Autores principales: Yang, Lan, Li, Hao, Han, Yao, Song, Yingjie, Wei, Mingchen, Fang, Mengya, Sun, Yansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138046/
https://www.ncbi.nlm.nih.gov/pubmed/37107564
http://dx.doi.org/10.3390/genes14040806

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