RNA Sequencing in Hypoxia-Adapted T98G Glioblastoma Cells Provides Supportive Evidence for IRE1 as a Potential Therapeutic Target

Glioblastoma (GBM) is an aggressive brain cancer with a median survival time of 14.6 months after diagnosis. GBM cells have altered metabolism and exhibit the Warburg effect, preferentially producing lactate under aerobic conditions. After standard-of-care treatment for GBM, there is an almost 100%...

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Detalles Bibliográficos
Autores principales: White, Brian E., Liu, Yichuan, Hakonarson, Hakon, Buono, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138146/
https://www.ncbi.nlm.nih.gov/pubmed/37107600
http://dx.doi.org/10.3390/genes14040841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138146/
https://www.ncbi.nlm.nih.gov/pubmed/37107600
http://dx.doi.org/10.3390/genes14040841

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