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Maximal interferon induction by influenza lacking NS1 is infrequent owing to requirements for replication and export

Influenza A virus exhibits high rates of replicative failure due to a variety of genetic defects. Most influenza virions cannot, when acting as individual particles, complete the entire viral life cycle. Nevertheless influenza is incredibly successful in the suppression of innate immune detection an...

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Detalles Bibliográficos
Autores principales: Vicary, Alison C., Mendes, Marisa, Swaminath, Sharmada, Lekbua, Asama, Reddan, Jack, Rodriguez, Zaida K., Russell, Alistair B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138204/
https://www.ncbi.nlm.nih.gov/pubmed/37068114
http://dx.doi.org/10.1371/journal.ppat.1010943