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Modulation of GCN2/eIF2α/ATF4 Pathway in the Liver and Induction of FGF21 in Young Goats Fed a Protein- and/or Phosphorus-Reduced Diet

Mammals respond to amino acid (AA) deficiency by initiating an AA response pathway (AAR) that involves the activation of general control nonderepressible 2 (GCN2), phosphorylation of eukaryotic translation initiation factor 2α (eIF2α), and activation of transcription factor 4 (ATF4). In this study,...

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Detalles Bibliográficos
Autores principales: Weber, Sarah L., Hustedt, Karin, Schnepel, Nadine, Visscher, Christian, Muscher-Banse, Alexandra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138370/
https://www.ncbi.nlm.nih.gov/pubmed/37108315
http://dx.doi.org/10.3390/ijms24087153