Cargando…

Modulation of GCN2/eIF2α/ATF4 Pathway in the Liver and Induction of FGF21 in Young Goats Fed a Protein- and/or Phosphorus-Reduced Diet

Mammals respond to amino acid (AA) deficiency by initiating an AA response pathway (AAR) that involves the activation of general control nonderepressible 2 (GCN2), phosphorylation of eukaryotic translation initiation factor 2α (eIF2α), and activation of transcription factor 4 (ATF4). In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weber, Sarah L., Hustedt, Karin, Schnepel, Nadine, Visscher, Christian, Muscher-Banse, Alexandra S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138370/ https://www.ncbi.nlm.nih.gov/pubmed/37108315 http://dx.doi.org/10.3390/ijms24087153

Ejemplares similares

Modulation of Intestinal Phosphate Transport in Young Goats Fed a Low Phosphorus Diet
por: Behrens, Joie L., et al.
Publicado: (2021)

Modulation of growth hormone receptor-insulin-like growth factor 1 axis by dietary protein in young ruminants
por: Firmenich, Caroline S., et al.
Publicado: (2020)

Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2α/ATF4 Pathway
por: Carraro, Valérie, et al.
Publicado: (2010)

ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
por: Yang, Shao-Ying, et al.
Publicado: (2023)

FGF21, not GCN2, influences bone morphology due to dietary protein restrictions
por: McNulty, Margaret A., et al.
Publicado: (2019)

ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress
por: Wan, Xiao-shan, et al.
Publicado: (2014)

Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK
por: Anderson, Bart R., et al.
Publicado: (2012)

Involvement of the eIF2α Kinase GCN2 in UV-B Responses
por: Llabata, Paula, et al.
Publicado: (2019)

Corrigendum to “ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress”
por: Wan, Xiao-shan, et al.
Publicado: (2018)

Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway
por: Wang, Sheng-Fan, et al.
Publicado: (2016)

Expression of Tight Junction Proteins and Cadherin 17 in the Small Intestine of Young Goats Offered a Reduced N and/or Ca Diet
por: Elfers, Kristin, et al.
Publicado: (2016)

GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
por: Cordova, Ricardo A, et al.
Publicado: (2022)

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway
por: Chen, Meng-Shian, et al.
Publicado: (2017)

Arabidopsis eIF2α kinase GCN2 is essential for growth in stress conditions and is activated by wounding
por: Lageix, Sébastien, et al.
Publicado: (2008)

Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae
por: Zaborske, John M, et al.
Publicado: (2010)

Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2
por: Baker, Brooke M., et al.
Publicado: (2012)

Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress
por: Misra, Jagannath, et al.
Publicado: (2021)

Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway
por: Chaveroux, Cédric, et al.
Publicado: (2016)

TM-25659-Induced Activation of FGF21 Level Decreases Insulin Resistance and Inflammation in Skeletal Muscle via GCN2 Pathways
por: Jung, Jong Gab, et al.
Publicado: (2015)

ERH Interacts With EIF2α and Regulates the EIF2α/ATF4/CHOP Pathway in Bladder Cancer Cells
por: Pang, Kun, et al.
Publicado: (2022)

HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2
por: Peidis, Philippos, et al.
Publicado: (2010)

Deletion of the eIF2α Kinase GCN2 Fails to Rescue the Memory Decline Associated with Alzheimer’s Disease
por: Devi, Latha, et al.
Publicado: (2013)

Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii
por: Augusto, Leonardo, et al.
Publicado: (2019)

Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2α pathway
por: Romero, Antonia María, et al.
Publicado: (2020)

The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
por: Stonyte, Vilte, et al.
Publicado: (2023)

4E-BP is a target of the GCN2–ATF4 pathway during Drosophila development and aging
por: Kang, Min-Ji, et al.
Publicado: (2017)

GCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism
por: Averous, Julien, et al.
Publicado: (2016)

Amino acid deprivation induces AKT activation by inducing GCN2/ATF4/REDD1 axis
por: Jin, Hyeon-Ok, et al.
Publicado: (2021)

INCREASED LIFESPAN THROUGH ALTERED GCN4 / ATF-5 IN S. CEREVISIAE AND C. ELEGANS
por: McCormick, Mark, et al.
Publicado: (2019)

Enhanced Interaction between Pseudokinase and Kinase Domains in Gcn2 stimulates eIF2α Phosphorylation in Starved Cells
por: Lageix, Sebastien, et al.
Publicado: (2014)

Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis
por: Dias-Teixeira, Karina Luiza, et al.
Publicado: (2017)

Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake
por: Pineda, Carmen, et al.
Publicado: (2018)

FGF21 induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathway
por: Joe, Yeonsoo, et al.
Publicado: (2018)

HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection
por: Jiang, Guochun, et al.
Publicado: (2017)

Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program
por: Srinivasan, Rajalakshmi, et al.
Publicado: (2020)

Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection
por: Bretin, Alexis, et al.
Publicado: (2016)

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
por: B’chir, Wafa, et al.
Publicado: (2013)

Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation
por: Yuan, Feixiang, et al.
Publicado: (2020)

Translational induction of ATF4 during integrated stress response requires noncanonical initiation factors eIF2D and DENR
por: Vasudevan, Deepika, et al.
Publicado: (2020)

Reciprocal regulation between GCN2 (eIF2AK4) and PERK (eIF2AK3) through the JNK-FOXO3 axis to modulate cancer drug resistance and clonal survival
por: Alasiri, Glowi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d97hgpi684t459he0em79h9opm