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Deficiency of AP1 Complex Ap1g1 in Zebrafish Model Led to Perturbation of Neurodevelopment, Female and Male Fertility; New Insight to Understand Adaptinopathies

In vertebrates, two homologous heterotetrameric AP1 complexes regulate the intracellular protein sorting via vesicles. AP-1 complexes are ubiquitously expressed and are composed of four different subunits: γ, β1, μ1 and σ1. Two different complexes are present in eukaryotic cells, AP1G1 (contains γ1...

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Detalles Bibliográficos
Autores principales: Mignani, Luca, Facchinello, Nicola, Varinelli, Marco, Massardi, Elena, Tiso, Natascia, Ravelli, Cosetta, Mitola, Stefania, Schu, Peter, Monti, Eugenio, Finazzi, Dario, Borsani, Giuseppe, Zizioli, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138411/
https://www.ncbi.nlm.nih.gov/pubmed/37108275
http://dx.doi.org/10.3390/ijms24087108