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Placental Remote Control of Fetal Metabolism: Trophoblast mTOR Signaling Regulates Liver IGFBP-1 Phosphorylation and IGF-1 Bioavailability

The mechanisms mediating the restricted growth in intrauterine growth restriction (IUGR) remain to be fully established. Mechanistic target of rapamycin (mTOR) signaling functions as a placental nutrient sensor, indirectly influencing fetal growth by regulating placental function. Increased secretio...

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Detalles Bibliográficos
Autores principales: Rosario, Fredrick J., Chopra, Anand, Biggar, Kyle, Powell, Theresa L., Gupta, Madhulika B., Jansson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138459/
https://www.ncbi.nlm.nih.gov/pubmed/37108437
http://dx.doi.org/10.3390/ijms24087273