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Chronological Age and DNA Damage Accumulation in Blood Mononuclear Cells: A Linear Association in Healthy Humans after 50 Years of Age

Aging is characterized by the progressive deregulation of homeostatic mechanisms causing the accumulation of macromolecular damage, including DNA damage, progressive decline in organ function and chronic diseases. Since several features of the aging phenotype are closely related to defects in the DN...

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Detalles Bibliográficos
Autores principales: Vlachogiannis, Nikolaos I., Ntouros, Panagiotis A., Pappa, Maria, Kravvariti, Evrydiki, Kostaki, Evangelia Georgia, Fragoulis, Georgios E., Papanikolaou, Christina, Mavroeidi, Dimitra, Bournia, Vasiliki-Kalliopi, Panopoulos, Stylianos, Laskari, Katerina, Arida, Aikaterini, Gorgoulis, Vassilis G., Tektonidou, Maria G., Paraskevis, Dimitrios, Sfikakis, Petros P., Souliotis, Vassilis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138488/
https://www.ncbi.nlm.nih.gov/pubmed/37108309
http://dx.doi.org/10.3390/ijms24087148