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Altered Brain Expression of DNA Methylation and Hydroxymethylation Epigenetic Enzymes in a Rat Model of Neuropathic Pain

The role of epigenetics in chronic pain at the supraspinal level is yet to be fully characterized. DNA histone methylation is crucially regulated by de novo methyltransferases (DNMT1-3) and ten-eleven translocation dioxygenases (TET1-3). Evidence has shown that methylation markers are altered in dif...

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Detalles Bibliográficos
Autores principales: Rodrigues, Diogo, Monteiro, Clara, Cardoso-Cruz, Helder, Galhardo, Vasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138521/
https://www.ncbi.nlm.nih.gov/pubmed/37108466
http://dx.doi.org/10.3390/ijms24087305