Autophagy in Spinocerebellar Ataxia Type 3: From Pathogenesis to Therapeutics

Machado–Joseph disease (MJD) or spinocerebellar ataxia 3 (SCA3) is a rare, inherited, monogenic, neurodegenerative disease, and the most common SCA worldwide. MJD/SCA3 causative mutation is an abnormal expansion of the triplet CAG at exon 10 within the ATXN3 gene. The gene encodes for ataxin-3, whic...

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Detalles Bibliográficos
Autores principales: Paulino, Rodrigo, Nóbrega, Clévio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138583/
https://www.ncbi.nlm.nih.gov/pubmed/37108570
http://dx.doi.org/10.3390/ijms24087405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138583/
https://www.ncbi.nlm.nih.gov/pubmed/37108570
http://dx.doi.org/10.3390/ijms24087405

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