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PDGF Receptors and Signaling Are Required for 3D-Structure Formation and Differentiation of Human iPSC-Derived Hepatic Spheroids

Human iPSC-derived liver organoids (LO) or hepatic spheroids (HS) have attracted widespread interest, and the numerous studies on them have recently provided various production protocols. However, the mechanism by which the 3D structures of LO and HS are formed from the 2D-cultured cells and the mec...

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Detalles Bibliográficos
Autores principales: Tsuzuki, Syusaku, Yamaguchi, Tomoyuki, Okumura, Takashi, Kasai, Toshiharu, Ueno, Yasuharu, Taniguchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138705/
https://www.ncbi.nlm.nih.gov/pubmed/37108241
http://dx.doi.org/10.3390/ijms24087075